Biochemical Reagents
Medchemexpress LLC Harmane-d1 | 486-84-0 | 98.0% | 183.23 | C12H9DN2 | 10 MG
Harmane-d1 is the deuterium-labeled isotopic standard of harmane supplied as a solid for laboratory research. It is intended for use as an analytical reference or tracer in studies involving imidazoline, adrenergic, and monoamine oxidase biology, and is provided in milligram-scale packaging for analytical applications.
- Deuterium-labeled isotopic standard for harmane.
- High purity (98.0%) suitable for analytical use.
- Molecular weight 183.23 g/mol and formula C12H9DN2.
- Provided as a solid in a 10 mg quantity.
- Documentation includes data sheet and safety data sheet.
Creative Biomart Liraglutide, GLP-1 peptide
The product, an analog of human GLP-1 and acts as a GLP-1 receptor agonist. The peptide precursor of the product, produced by a process that includes expression of recombinant DNA in Saccharomyces cerevisiae, has been engineered to be 97% homologous to native human GLP-1 by substituting arginine for lysine at position 34. The product is made by attaching a C-16 fatty acid (palmitic acid) with a glutamic acid spacer on the remaining lysine residue at position 26 of the peptide precursor.
ABclonal Technology Acetyl-Histone H4-K8 Rabbit pAb
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H4 family. Transcripts from this gene lack polyA tails, instead, they contain a palindromic termination element. This gene is found in a histone cluster on chromosome 1. This gene is one of four histone genes in the cluster that are duplicated, this record represents the centromeric copy.
Bachem Atrial Natriuretic Factor (1-28) (mouse, rabbit, rat) Trifluoroacetate
Atrial Natriuretic Factor (1-28) (mouse, rabbit, rat) Trifluoroacetate, H-Ser-Leu-Arg-Arg-Ser-Ser-Cys-Phe-Gly-Gly-Arg-Ile-Asp-Arg-Ile-Gly-Ala-Gln-Ser-Gly-Leu-Gly-Cys-Asn-Ser-Phe-Arg-Tyr-OH, 88898-17-3, C128H205N45O39S2, Mr 3062.45, 1mg. rANF (1-28), Atrial Natriuretic Peptide (1-28), rat.
CPC Scientific H-Phe-Leu-Phe-Gln-Pro-Gln-Arg-Phe-NH2 (trifluoroacetate salt) 1MG
This peptide has been isolated from the bovine central nervous system, which implicated in a variety of physiological functions, including nociception, cardiovascular responses, and neuroendocrine regulation.ONE-LETTER SEQUENCE: FLFQPQRF-NH2MOLECULAR FORMULA: C54H76N14O10MOLECULAR WEIGHT:1081.29STORAGE CONDITIONS: -20 5C, CAS REGISTRY NUMBER: [99566-27-5], RESEARCH AREA: NeuropeptidesREFERENCES: M.Xu et al., Peptides, 22, 33 (2001); C.Mollereau et al., Pharmacol. Rep., 63, 1061 (2011)
Medchemexpress LLC M617 TFA | 99.4% | 2475.67 | 5 MG
M617 TFA is a selective galanin receptor 1 (GAL1) agonist that promotes GLUT4 expression and enhances GLUT4 content in cardiac muscle of type 2 diabetic rats. It has a high selectivity with Kis of 0.23 nM for GAL1 and 5.71 nM for GAL2.
- Selective galanin receptor 1 (GAL1) agonist
- Promotes GLUT4 expression
- Enhances GLUT4 content in cardiac muscle
- Molecular weight of 2475.67
- Molecular formula C114H162F3N29O30
- Purity of 99.38% (LCMS)
- White to off-white solid appearance
Medchemexpress LLC HY-P1244A 1mg Medchemexpress, Secretin (33-59), rat (TFA) CAS: Purity:>98%
Medchemexpress, HY-P1244A 1mg Secretin (33-59), rat (TFA) CAS: Secretin (33-59), rat (TFA) is a 27-aa peptide, which acts on secretin receptor, and enhances the secretion of bicarbonate, enzymes, and K+ from the pancreas. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
CPC Scientific H-Gly-Trp-Thr-Leu-Asn-Ser-Ala-Gly-Tyr-Leu-Leu-Gly-Pro-Pro-Pro-Ala-Leu-Ala-Leu-Ala-NH2 (trifluoroacetate salt) 0.5MG
Antagonist of galanin receptor that significantly antagonizes galanin-induced feeding behavior at doses approximately equimolar to the active doses of rat galanin. It inhibits the binding of (125I-Tyr26)-galanin (porcine) in rat hypothalamic membranes with IC50 value of 15nM. ONE-LETTER SEQUENCE: GWTLNSAGYLLGPPPALALA-NH2MOLECULAR FORMULA: C94H145N23O24MOLECULAR WEIGHT:1981.33STORAGE CONDITIONS: -20 5C, CAS REGISTRY NUMBER: [143896-17-7], SYNONYMS: Galanin (1-13)-Pro-Pro-(Ala-Leu-)Ala amide RESEARCH AREA: Alzheimer's DiseaseREFERENCES: S.F. Leibowitz et al., Brain Res., 599, 148 (1992); J.N. Crawley et al., Brain Res., 600, 268 (1993); X. J. Xu et al., Br. J. Pharmacol., 116, 2076 (1995)
CPC Scientific Biotin-Lys-Gly-Gly-His-Leu-Lys-Ser-Lys-Lys-Gly-Gln-Ser-Thr-Ser-Arg-His-Lys-Lys(Ac)-Leu-Met-Phe-Lys-Thr-Glu-Gly-Pro-Asp-Ser-Asp-NH2 (trifluoroacetate salt) 1MG
This peptide is tumor suppressor protein p53 (368-393). There is a biotinylated lysine follwed by a GG linker at the N-terminal and is acetylated at lysine 382. p53 is an ideal tumor suppressor gene because of its ability to control cell proliferation, and senescence. In response to cell stress, cell damage, or ectopic oncogene, p53 also mediates apoptosis.ONE-LETTER SEQUENCE: Biotin-KGGHLKSKKGQSTSRHK-K(Ac)-LMFKTEGPDSD-NH2MOLECULAR FORMULA: MOLECULAR WEIGHT:3481STORAGE CONDITIONS: -20 5CRESEARCH AREA: CancerREFERENCES: Ghosh, A. et al. Mol. Cell Biol. 24, 7987 (2004)
Bachem Fmoc-D-Asp(OtBu)-(Hmb)Gly-OH
Fmoc-D-Asp(OtBu)-(Hmb)Gly-OH, 1926163-00-9, C33H36N2O9, Mr 604.67, 1g. Fmoc-D-Asp(OtBu)-N-(2-hydroxy-4-methoxy-Bzl)-Gly-OH. A building block for the synthesis of peptides containing the D-Asp-Gly motif avoiding base-catalyzed aspartimide formation.
Medchemexpress LLC MC-Val-Cit-PAB-Auristatin E | 2055896-77-8 | 97.0% | 1287.65 g/mol | C68H108N11O13 | 1 MG
MC-Val-Cit-PAB-Auristatin E is an antibody-drug conjugate (ADC) drug-linker conjugate that links auristatin E to a cathepsin-cleavable MC-Val-Cit-PAB linker for use in ADC research and antitumor studies.
- Contains auristatin E as the cytotoxic payload.
- Features a cathepsin-cleavable Val-Cit-PAB linker for intracellular release.
- High purity suitable for research applications.
- Solid form with storage at 4°C to maintain stability.
- Available in small milligram pack sizes for pilot studies.
Genscript Corporation CD36/SR-B3 His Mouse
CD36 (cluster of differentiation 36) also known as platelet glycoprotein 4 is a protein that in humans is encoded by the CD36 gene The CD36 antigen is an integral membrane protein found on the surface of many cell types in vertebrate animals It imports fatty acids inside cells and is a member of the class B scavenger receptor family of cell surface proteins
CPC Scientific H-Tyr-Tic-Phe-Phe-OH (trifluoroacetate salt) 5MG
This peptide is a potent and highly selective antagonist at the delta-opioid receptor (IC50 = 6 nM) and therefore an ideal candidate for the study of opioid pharmacology (delta-opioid receptors).SEQUENCE: H-Tyr-Tic-Phe-Phe-OH (trifluoroacetate salt)ONE-LETTER SEQUENCE: Y-Tic-FFMOLECULAR FORMULA: C37H38N4O6MOLECULAR WEIGHT: 634.73STORAGE CONDITIONS: -20 5 CCAS REGISTRY NUMBER: [146369-65-5]SYNONYMS: RESEARCH AREA: PainREFERENCES:P.W.Schiller et al., Proc. Natl. Acad. Sci. USA, 89, 11871 (1992)V.Kumar et al., J. Med. Chem., 43, 5050 (2000)D.Y.Maeda et al., J. Med. Chem., 43, 5044 (2000)SKU(s): OPIO-013A, OPIO-014
Bachem Spexin Trifluoroacetate
Spexin Trifluoroacetate, H-Asn-Trp-Thr-Pro-Gln-Ala-Met-Leu-Tyr-Leu-Lys-Gly-Ala-Gln-NH2, 1370290-58-6, C74H114N20O19S, Mr 1619.91, 1mg. Spexin/NPQ human, mouse, bovine. Spexin (SPX, also called NPQ) is a gastro-intestinal peptide hormone. In situ hybridization localized its mRNA to the stomach and esophagus. Synthetic spexin induced dose-dependent contraction of stomach muscle, suggesting that it is involved in digestion. The results obtained by Rucinski et al. indicate that spexin may inhibit adrenocortical cell proliferation.